Barbara Irene Glasco passed away at 9:43 a.m. Tuesday, March 22, 2022, at her home surrounded by family. She was born June 28, 1935, at home in Ashland, IL, the daughter of Clyde and Lula Mae Clemons. She married Keith DuWayne Sr. on March 16, 1957, in Ashland. He preceded her in death on February 16, 2017. Barbara is survived by her two sons, DuWayne (Vicki) Glasco of Cobden, and Tim (Glenda) Glasco of Anna; grandsons, Greg Glasco of Cobden, Mark (Amy) Glasco of Cobden; granddaughters, Amanda Glasco of Jonesboro and Andrea Glasco, of Cobden, Tracy Glasco of Cobden, Lauren (Eric) Myers of Cobden; numerous great-grandchildren; sister Karen (Jim) Barnhart; nieces and nephews; and many other relatives and friends. She was preceded in death by both of her parents and her brother, Willie Clemons. Barbara was an active member of the United Missionary Baptist Church for many years. She was a much loved wife, "mom" and grandma to her entire family. Every person she met has a story to tell about how she touched their life. When she wasn't watching her "kids" or "grandkids" rodeo or play sports, you could find her at her kitchen table on the hill of her beautiful Southern Illinois farm with her loyal dog, Hash. Funeral services for Mrs. Barbara I. Glasco will be at 1:00 p.m. Thursday, March 24, 2022 at the Rendleman and Hileman Funeral Home in Jonesboro with the Rev. Paul Sadler officiating. Interment will be in Ebenezer Hall Cemetery. Friends may call after 11:00 a.m. and until the service hour at 1:00 p.m. Thursday at the funeral home. In lieu of flowers, memorials are preferred to the United Missionary Baptist Church or Hospice of Southern Illinois. Envelopes will be available at Rendleman and Hileman Funeral Home.